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PTCH2

Description patched 2
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Membrane
Molecular Function
  • Smoothened Binding
  • Hedgehog Receptor Activity
  • Hedgehog Family Protein Binding
Biological Process
  • Regulation Of Cell Growth
  • Cell Fate Determination
  • Smoothened Signaling Pathway
  • Epidermal Cell Fate Specification
  • Hair Cycle
  • Skin Development
  • Positive Regulation Of Epidermal Cell Differentiation
  • Negative Regulation Of Smoothened Signaling Pathway
Pathways
  • Class B/2 (Secretin family receptors)
Drugs
Diseases
  • Basal cell nevus syndrome; Nevoid basal cell carcinoma syndrome; Gorlin syndrome
GWAS
  • Intraocular pressure ( 30591961)
Interacting Genes 4 interacting genes: DHH IHH SHH SMO
Entrez ID 8643
HPRD ID 04722
Ensembl ID ENSG00000117425
Uniprot IDs Q9Y6C5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

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