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SPRTN

Description SprT-like N-terminal domain
Image
GO Annotations Cellular Component
  • Chromatin
  • Nucleus
  • Nucleoplasm
  • Nuclear Speck
Molecular Function
  • Double-stranded DNA Binding
  • Single-stranded DNA Binding
  • Metalloendopeptidase Activity
  • Protein Binding
  • Polyubiquitin Modification-dependent Protein Binding
  • Ubiquitin Binding
  • Metal Ion Binding
  • K63-linked Polyubiquitin Modification-dependent Protein Binding
Biological Process
  • Proteolysis
  • Cellular Response To DNA Damage Stimulus
  • Response To UV
  • Protein Autoprocessing
  • Translesion Synthesis
  • Positive Regulation Of Protein Ubiquitination
  • Error-free Translesion Synthesis
  • Protein-DNA Covalent Cross-linking Repair
Pathways
  • Translesion Synthesis by POLH
Drugs
Diseases
GWAS
  • Hematocrit ( 32888494)
  • Hemoglobin ( 32888494)
Interacting Genes 3 interacting genes: POLD3 RNF11 UBC
Entrez ID 83932
HPRD ID 13164
Ensembl ID ENSG00000010072
Uniprot IDs A0A024R3U2 Q9H040
PDB IDs 5IY4 6MDW 6MDX
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025