ZBP1

Description		Z-DNA binding protein 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	DNA Binding Left-handed Z-DNA Binding Double-stranded RNA Binding Protein Binding
	Biological Process	Activation Of Innate Immune Response Apoptotic Process Viral Process Regulation Of Type I Interferon Production Positive Regulation Of Type I Interferon Production Positive Regulation Of Apoptotic Process Innate Immune Response Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Defense Response To Virus Positive Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Necroptotic Process Pyroptosis Regulation Of Interleukin-1-mediated Signaling Pathway
Pathways		ZBP1(DAI) mediated induction of type I IFNs IRF3 mediated activation of type 1 IFN IRF3 mediated activation of type 1 IFN RIP-mediated NFkB activation via ZBP1 Regulation of innate immune responses to cytosolic DNA Potential therapeutics for SARS
Drugs
Diseases
GWAS		Hippocampal atrophy ( 19668339) Response to fenofibrate (adiponectin levels) ( 23149075) Verbal declarative memory ( 25648963)
Novel Interacting Genes		1 novel interacting genes: APOE
Interacting Genes		8 interacting genes: CTBP1 CTBP2 KLHL12 PALD1 PLXDC2 SIAH1 TRAF3 TRIP6
Entrez ID		81030
HPRD ID		09484
Ensembl ID		ENSG00000124256
Uniprot IDs		Q9H171
PDB IDs		2L4M 2LNB 3EYI 4KA4
Enriched GO Terms of Interacting Partners?
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