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USP5

Description ubiquitin specific peptidase 5
Image
GO Annotations Cellular Component
  • Nucleus
  • Lysosome
  • Cytosol
Molecular Function
  • Cysteine-type Endopeptidase Activity
  • Thiol-dependent Ubiquitin-specific Protease Activity
  • Protein Binding
  • Zinc Ion Binding
  • Ubiquitin Binding
Biological Process
  • Ubiquitin-dependent Protein Catabolic Process
  • Protein Ubiquitination
  • Protein Deubiquitination
  • Protein Phosphopantetheinylation
  • Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Protein K48-linked Deubiquitination
Pathways
  • Ub-specific processing proteases
  • Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Drugs
Diseases
GWAS
  • Refractive error ( 32231278)
Interacting Genes 26 interacting genes: APP DAZAP2 DVL2 PJA1 PLA2G2A RFFL RNF11 RNF216 SMURF1 SPART STK33 SUMO2 TADA3 TMEM239 TRIM26 TRIM39 TRIM5 TRIM54 TRIM55 TRIM63 TRIM8 TRIML1 UBC UBE2S UBTD2 USP28
Entrez ID 8078
HPRD ID 03265
Ensembl ID ENSG00000111667
Uniprot IDs A0A140VJZ1 P45974
PDB IDs 2DAG 2DAK 2G43 2G45 3IHP 6DXH 6DXT 6NFT 6P9G
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025