NEIL1

Description		nei like DNA glycosylase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytoplasm Microtubule Organizing Center
	Molecular Function	Damaged DNA Binding DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Protein C-terminus Binding Zinc Ion Binding Hydrolase Activity, Acting On Glycosyl Bonds DNA N-glycosylase Activity Class I DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity
	Biological Process	Base-excision Repair Response To Oxidative Stress Negative Regulation Of Nuclease Activity Depyrimidination
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway Defective Base Excision Repair Associated with NEIL1
Drugs		Iron Copper Ferrous gluconate Ferrous succinate Ferrous ascorbate Ferrous fumarate Ferrous glycine sulfate
Diseases
GWAS
Novel Interacting Genes		1 novel interacting genes: MAP3K11
Interacting Genes		6 interacting genes: APP HUS1 LIG3 POLB RAD1 XRCC1
Entrez ID		79661
HPRD ID		12314
Ensembl ID		ENSG00000140398
Uniprot IDs		Q96FI4
PDB IDs		1TDH 4NRV 5ITQ 5ITR 5ITT 5ITU 5ITX 5ITY
Enriched GO Terms of Interacting Partners?
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