ZIC3

Description		Zic family member 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Heart Looping Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Central Nervous System Development Anterior/posterior Pattern Specification Cell Differentiation Lung Development Somatic Stem Cell Population Maintenance Determination Of Pancreatic Left/right Asymmetry Determination Of Left/right Asymmetry In Nervous System Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Determination Of Digestive Tract Left/right Asymmetry Determination Of Liver Left/right Asymmetry
Pathways		POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Transcriptional regulation of pluripotent stem cells
Drugs
Diseases		Heterotaxy; Situs ambiguus
GWAS		Refractive error ( 32231278)
Novel Interacting Genes		2 novel interacting genes: DNAI1 POFUT1
Interacting Genes		5 interacting genes: CTNNB1 GLI3 SRF TP53 TWIST1
Entrez ID		7547
HPRD ID		02225
Ensembl ID		ENSG00000156925
Uniprot IDs		O60481
PDB IDs		2EJ4 2RPC
Enriched GO Terms of Interacting Partners?
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