C8B

Description		complement C8 beta chain
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GO Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Membrane Extracellular Exosome Extracellular Vesicle
	Molecular Function	Protein-containing Complex Binding
	Biological Process	Immune Response Complement Activation Complement Activation, Alternative Pathway Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation
Pathways		Terminal pathway of complement Regulation of Complement cascade
Drugs		Zinc Copper Zinc acetate
Diseases		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS		Blood protein levels ( 29875488 28240269) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		3 interacting genes: C5 C8A CLU
Entrez ID		732
HPRD ID		00410
Ensembl ID		ENSG00000021852
Uniprot IDs		B7Z550 B7Z555 P07358
PDB IDs		3OJY 6H03 6H04
Enriched GO Terms of Interacting Partners?
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