C4BPA

Description		complement component 4 binding protein alpha
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Blood Microparticle
	Molecular Function	RNA Binding Protein Binding
	Biological Process	Complement Activation, Classical Pathway Response To Symbiotic Bacterium Regulation Of Complement Activation Innate Immune Response Positive Regulation Of Protein Catabolic Process Negative Regulation Of Complement Activation, Classical Pathway Regulation Of Opsonization
Pathways		Regulation of Complement cascade
Drugs		Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases		Complement regulatory protein defects, including the following six diseases: C1 inhibitor deficiency (hereditary angioedema); C4 binding protein alpha deficiency; C4 binding protein beta deficiency; Factor I deficiency; Decay-accelerating factor (CD55) deficiency; CD59 deficiency
GWAS		Blood protein levels ( 29875488) C4b binding protein levels ( 20212171) Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 32888494) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Venous thromboembolism ( 31420334 31676865)
Interacting Genes		9 interacting genes: APCS BMPR2 FXYD6 GIT2 GTF2I LBP LRP1 PROS1 SMARCD1
Entrez ID		722
HPRD ID		00403
Ensembl ID		ENSG00000123838
Uniprot IDs		P04003
PDB IDs		2A55 4B0F 5HYP 5HYT 5HYU 5HZP 5I0Q
Enriched GO Terms of Interacting Partners?
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