TLL1

Description		tolloid like 1
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GO Annotations	Cellular Component	Extracellular Region
	Molecular Function	Metalloendopeptidase Activity Calcium Ion Binding Zinc Ion Binding
	Biological Process	Skeletal System Development Proteolysis Extracellular Matrix Disassembly Cell Differentiation
Pathways		Degradation of the extracellular matrix Collagen biosynthesis and modifying enzymes Anchoring fibril formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (sporadic) ( 24529757) Body mass index ( 28552196) Bone mineral density change response to combined chemotherapy in acute lymphoblastic leukemia ( 29266176) Cerebrospinal fluid clusterin levels ( 26545630) Glomerular filtration rate in chronic kidney disease ( 26420894) Hepatocellular carcinoma in post hepatitis C eradication by interferon therapy ( 28163062) Hip circumference adjusted for BMI ( 28552196) Intraocular pressure ( 29785010) Multiple sclerosis ( 23412934) Obesity-related traits ( 23251661) Post-traumatic stress disorder ( 23726511) Post-traumatic stress disorder (asjusted for relatedness) ( 23726511) Refractive error ( 32231278) Response to hepatitis B vaccine ( 29534301) Serum bilirubin levels in metabolic syndrome ( 30621171) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist-to-hip ratio adjusted for BMI ( 28552196) Weight ( 28552196) Western dietary pattern ( 28644415)
Interacting Genes		2 interacting genes: APP CHRD
Entrez ID		7092
HPRD ID		07074
Ensembl ID		ENSG00000038295
Uniprot IDs		B7ZLW3 O43897
PDB IDs		3EDI
Enriched GO Terms of Interacting Partners?
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