CDKL5

Description		cyclin dependent kinase like 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Centrosome Ruffle Membrane Dendrite Cytoplasm Ciliary Basal Body Dendritic Growth Cone Perinuclear Region Of Cytoplasm Ciliary Tip Glutamatergic Synapse Postsynaptic Density, Intracellular Component
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Small GTPase Binding
	Biological Process	Neuron Migration Protein Phosphorylation Positive Regulation Of GTPase Activity Positive Regulation Of Axon Extension Protein Autophosphorylation Regulation Of Dendrite Development Positive Regulation Of Dendrite Morphogenesis Regulation Of Cell Cycle Positive Regulation Of Dendritic Spine Development Regulation Of Postsynapse Organization Regulation Of Cilium Assembly
Pathways
Drugs
Diseases		Early infantile epileptic encephalopathy; Ohtahara syndrome Prader-Willi and Angelman syndromes, including: Angelman syndrome (AS); Prader-Willi syndrome (PWS)
GWAS		Estimated glomerular filtration rate ( 31015462)
Interacting Genes		2 interacting genes: MLH1 SKIV2L
Entrez ID		6792
HPRD ID		02190
Ensembl ID		ENSG00000008086
Uniprot IDs		O76039
PDB IDs		4BGQ
Enriched GO Terms of Interacting Partners?
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