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BMX

Description BMX non-receptor tyrosine kinase
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytosol
  • Plasma Membrane
  • Ruffle Membrane
Molecular Function
  • Protein Tyrosine Kinase Activity
  • Non-membrane Spanning Protein Tyrosine Kinase Activity
  • Protein Binding
  • ATP Binding
  • Metal Ion Binding
Biological Process
  • Adaptive Immune Response
  • Protein Phosphorylation
  • Phosphatidylinositol Biosynthetic Process
  • Apoptotic Process
  • Cell Adhesion
  • Signal Transduction
  • Mesoderm Development
  • Intracellular Signal Transduction
  • Peptidyl-tyrosine Autophosphorylation
  • Protein Autophosphorylation
  • B Cell Receptor Signaling Pathway
Pathways
  • Apoptotic cleavage of cellular proteins
  • Synthesis of PIPs at the plasma membrane
Drugs
  • Fostamatinib
  • Zanubrutinib
Diseases
GWAS
Interacting Genes 26 interacting genes: APP BCAR1 BIRC2 BTK CASP3 CAV1 CLNK EGFR ERBB2 FBXO25 ITK KDR NOPCHAP1 PAK1 PTK2 PTPN21 PTPRD RAP1A RUFY1 RUFY2 SRC STAT1 STAT3 STAT5A TEC TNFRSF1B
Entrez ID 660
HPRD ID 02111
Ensembl ID ENSG00000102010
Uniprot IDs P51813
PDB IDs 2EKX 2YS2 3SXR 3SXS 6I99
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025