SLC6A2

Description		solute carrier family 6 member 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Membrane Neuronal Cell Body Membrane Presynaptic Membrane Neuron Projection Membrane Raft
	Molecular Function	Actin Binding Neurotransmitter Transmembrane Transporter Activity Neurotransmitter:sodium Symporter Activity Dopamine:sodium Symporter Activity Norepinephrine:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Alpha-tubulin Binding Metal Ion Binding Beta-tubulin Binding
	Biological Process	Neurotransmitter Transport Chemical Synaptic Transmission Monoamine Transport Norepinephrine Transport Sodium Ion Transmembrane Transport Response To Drug Response To Pain Dopamine Uptake Involved In Synaptic Transmission Norepinephrine Uptake Neuron Cellular Homeostasis
Pathways		Na+/Cl- dependent neurotransmitter transporters Defective SLC6A2 causes orthostatic intolerance (OI)
Drugs		Amphetamine Phentermine Tramadol Guanadrel Reboxetine Benzatropine Venlafaxine Atomoxetine Amitriptyline Protriptyline Loxapine Methylphenidate Meperidine Imipramine Duloxetine Dextromethorphan Nortriptyline Amoxapine Mazindol Paroxetine Trimipramine Phenmetrazine Pseudoephedrine Cocaine Cyclobenzaprine Maprotiline Diethylpropion Dopamine Sertraline Sibutramine Chlorpheniramine Doxepin Nefazodone Desipramine Bupropion Guanethidine Orphenadrine Escitalopram Ketamine Clomipramine Ephedra sinica root Ephedrine Ginkgo biloba MMDA Midomafetamine Dextroamphetamine Metamfetamine Phendimetrazine Nomifensine Amineptine Debrisoquine Bicifadine Milnacipran XEN2174 DDP-225 CRx-119 Amitifadine Mianserin Tesofensine Tapentadol Trodusquemine Desvenlafaxine Dexmethylphenidate Levomilnacipran Vortioxetine Dosulepin Viloxazine Zotepine Dasotraline Netarsudil Solriamfetol
Diseases		Orthostatic intolerance (OI); Postural tachycardia syndrome (POTS)
GWAS		Birth weight ( 31043758) Post bronchodilator FEV1 ( 26634245)
Novel Interacting Genes		1 novel interacting genes: RPGRIP1L
Interacting Genes		2 interacting genes: PPP2R1A STX1A
Entrez ID		6530
HPRD ID		01232
Ensembl ID		ENSG00000103546
Uniprot IDs		A0A024R6T9 H3BRE9 P23975
PDB IDs
Enriched GO Terms of Interacting Partners?
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