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RYK
Description
receptor like tyrosine kinase
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Membrane
Receptor Complex
Molecular Function
Protein Tyrosine Kinase Activity
Transmembrane Receptor Protein Tyrosine Kinase Activity
Transmembrane Signaling Receptor Activity
Frizzled Binding
Protein Binding
ATP Binding
Wnt-protein Binding
Wnt-activated Receptor Activity
Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway
Biological Process
Protein Phosphorylation
Signal Transduction
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Multicellular Organism Development
Axonogenesis
Axon Guidance
Synapse Assembly
Wnt Signaling Pathway
Peptidyl-tyrosine Phosphorylation
Neurogenesis
Corpus Callosum Development
Neuron Differentiation
Neuron Projection Development
Cell Proliferation In Midbrain
Positive Regulation Of Kinase Activity
Non-canonical Wnt Signaling Pathway
Chemorepulsion Of Dopaminergic Neuron Axon
Positive Regulation Of MAPK Cascade
Skeletal System Morphogenesis
Negative Regulation Of Axon Extension Involved In Axon Guidance
Canonical Wnt Signaling Pathway
Commissural Neuron Axon Guidance
Planar Cell Polarity Pathway Involved In Axon Guidance
Midbrain Dopaminergic Neuron Differentiation
Wnt Signaling Pathway Involved In Midbrain Dopaminergic Neuron Differentiation
Pathways
TCF dependent signaling in response to WNT
PCP/CE pathway
Drugs
Diseases
GWAS
Cadmium levels (
26025379
)
Diastolic blood pressure (
27841878
30578418
)
Height (
31562340
)
Systolic blood pressure (
28135244
27841878
)
Interacting Genes
8 interacting genes:
EPHB2
EPHB3
FZD8
PPM1B
PPP3CA
PTPRR
WNT1
WNT3A
Entrez ID
6259
HPRD ID
02751
Ensembl ID
ENSG00000163785
Uniprot IDs
P34925
Q59FQ5
Q8WTZ8
PDB IDs
6TUA
Enriched GO Terms of Interacting Partners
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Tagcloud
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