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RPL27A
Description
ribosomal protein L27a
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum
Cytosol
Membrane
Cytosolic Large Ribosomal Subunit
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Translation
Translational Initiation
SRP-dependent Cotranslational Protein Targeting To Membrane
Viral Transcription
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Body mass index (
26426971
20935630
28448500
)
Body mass index (age <50) (
26426971
)
Body mass index (joint analysis main effects and physical activity interaction) (
28448500
)
Body mass index in physically active individuals (
28448500
)
Body mass index x sex x age interaction (4df test) (
26426971
)
Fruit consumption (
32066663
)
Obesity (
23563607
)
Novel Interacting Genes
2 novel interacting genes:
ESR1
PTGES2
Interacting Genes
6 interacting genes:
DUX4
GTF2F2
PEX6
PRKACB
PTEN
SIAH1
Entrez ID
6157
HPRD ID
04701
Ensembl ID
ENSG00000166441
Uniprot IDs
P46776
PDB IDs
4BXF
4UG0
4V6X
5AJ0
5LKS
5T2C
6EK0
6IP5
6IP6
6IP8
6LQM
6LSR
6LSS
6LU8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6W6L
6XA1
6Y0G
6Y2L
6Y57
6Y6X
6Z6L
6Z6M
6Z6N
6ZM7
6ZME
6ZMI
6ZMO
Enriched GO Terms of Interacting Partners
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