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PLEKHA1
Description
pleckstrin homology domain containing A1
Image
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Ruffle Membrane
Extracellular Exosome
Molecular Function
Protein Binding
Lipid Binding
PDZ Domain Binding
Phosphatidylinositol-3,4-bisphosphate Binding
Biological Process
Luteinization
Phosphatidylinositol Biosynthetic Process
Spermatogenesis
Androgen Metabolic Process
Estrogen Metabolic Process
Post-embryonic Development
Phosphatidylinositol 3-kinase Signaling
Ruffle Organization
Leydig Cell Differentiation
Multicellular Organism Growth
Establishment Of Protein Localization
Platelet-derived Growth Factor Receptor Signaling Pathway
Skeletal System Morphogenesis
B Cell Receptor Signaling Pathway
Negative Regulation Of Protein Kinase B Signaling
Roof Of Mouth Development
Face Morphogenesis
Cellular Response To Hydrogen Peroxide
Pathways
Synthesis of PIPs at the plasma membrane
Drugs
Citric acid
Diseases
GWAS
Age-related macular degeneration (
23577725
23536807
)
Age-related macular degeneration (extreme sampling) (
23577725
)
Autoimmune thyroid disease (
32581359
)
Birth weight (
31043758
27680694
)
Central corneal thickness (
32528159
)
Femoral neck bone mineral density (
29499414
)
Height (
31562340
20189936
)
Medication use (thyroid preparations) (
31015401
)
Offspring birth weight (
31043758
)
Refractive error (
32231278
)
Type 1 diabetes in high risk HLA genotype individuals (time to event) (
29310926
)
Type 2 diabetes (
28566273
24509480
30054458
30297969
32499647
30718926
28869590
)
Novel Interacting Genes
1 novel interacting genes:
ATE1
Interacting Genes
8 interacting genes:
CLDN14
CRKL
FBXO7
MPDZ
PLEKHA2
PTPN13
SH3BP4
SNTG1
Entrez ID
59338
HPRD ID
09686
Ensembl ID
ENSG00000107679
Uniprot IDs
B3KQL5
Q5RGS4
Q9HB21
PDB IDs
1EAZ
Enriched GO Terms of Interacting Partners
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