ALS2

Description		alsin Rho guanine nucleotide exchange factor ALS2
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleus Early Endosome Centrosome Cytosol Lamellipodium Dendrite Growth Cone Vesicle Protein-containing Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding Small GTPase Binding Identical Protein Binding Protein Homodimerization Activity Protein Serine/threonine Kinase Activator Activity
	Biological Process	Endosome Organization Lysosomal Transport Positive Regulation Of Rac Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase Activity Neuron Projection Morphogenesis Regulation Of Endosome Size Protein Homooligomerization Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease Juvenile primary lateral sclerosis
GWAS		Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Perceived intensity of sweet substances ( 31005972)
Novel Interacting Genes		3 novel interacting genes: IMPDH2 PPIL3 SUN2
Interacting Genes		1 interacting genes: YWHAB
Entrez ID		57679
HPRD ID		05893
Ensembl ID		ENSG00000003393
Uniprot IDs		A8K4R4 Q96Q42
PDB IDs
Enriched GO Terms of Interacting Partners?
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