NUDT15

Description		nudix hydrolase 15
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	Protein Binding 8-oxo-7,8-dihydroguanosine Triphosphate Pyrophosphatase Activity Nucleoside-diphosphatase Activity NADH Pyrophosphatase Activity 8-oxo-7,8-dihydrodeoxyguanosine Triphosphate Pyrophosphatase Activity DTTP Diphosphatase Activity Metal Ion Binding Nucleoside-triphosphate Diphosphatase Activity
	Biological Process	Mitotic Cell Cycle Response To Reactive Oxygen Species Purine Nucleotide Catabolic Process DGTP Catabolic Process Nucleobase-containing Small Molecule Catabolic Process DNA Protection Exogenous Drug Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Nucleoside Phosphate Catabolic Process
Pathways		Phosphate bond hydrolysis by NUDT proteins
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 27558924 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122)
Novel Interacting Genes		4 novel interacting genes: CDADC1 FNDC3A MTRF1 UTP14C
Interacting Genes		2 interacting genes: GABARAPL2 SRD5A3
Entrez ID		55270
HPRD ID		14848
Ensembl ID		ENSG00000136159
Uniprot IDs		Q9NV35
PDB IDs		5BON 5LPG 6T5J
Enriched GO Terms of Interacting Partners?
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