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SERPINF2
Description
serpin family F member 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Fibrinogen Complex
Extracellular Space
Cell Surface
Platelet Alpha Granule Lumen
Collagen-containing Extracellular Matrix
Extracellular Exosome
Blood Microparticle
Molecular Function
Protease Binding
Endopeptidase Inhibitor Activity
Serine-type Endopeptidase Inhibitor Activity
Protein Binding
Protein Homodimerization Activity
Biological Process
Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin
Platelet Degranulation
Acute-phase Response
Response To Organic Substance
Negative Regulation Of Plasminogen Activation
Negative Regulation Of Endopeptidase Activity
Collagen Fibril Organization
Positive Regulation Of Collagen Biosynthetic Process
Fibrinolysis
Positive Regulation Of Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of JNK Cascade
Blood Vessel Morphogenesis
Positive Regulation Of Smooth Muscle Cell Proliferation
Positive Regulation Of Stress Fiber Assembly
Negative Regulation Of Fibrinolysis
Positive Regulation Of ERK1 And ERK2 Cascade
Positive Regulation Of Transforming Growth Factor Beta Production
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways
Platelet degranulation
Dissolution of Fibrin Clot
Drugs
Ocriplasmin
Copper
Diseases
Alpha-2-plasmin inhibitor (a2-PI) deficiency
GWAS
Blood protein levels (
29875488
)
Calcium levels (
24068962
20705733
)
Serum albumin level (
23022100
29403010
)
Urate levels (
31578528
)
Novel Interacting Genes
1 novel interacting genes:
MYH10
Interacting Genes
17 interacting genes:
BCAP31
CFD
CTRB1
DEFA1
ELANE
F11
F13A1
FGA
KLK13
KLK2
KLK6
PLAU
PLG
PRSS1
SERPINB12
SSR1
TGM2
Entrez ID
5345
HPRD ID
02029
Ensembl ID
ENSG00000167711
Uniprot IDs
P08697
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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