TRIM33

Description		tripartite motif containing 33
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GO Annotations	Cellular Component	Nucleus Nucleoplasm
	Molecular Function	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Co-SMAD Binding R-SMAD Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Ubiquitination Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Transcription, DNA-templated
Pathways		Downregulation of SMAD2/3:SMAD4 transcriptional activity
Drugs
Diseases
GWAS		Autism ( 24189344) Carotid intima media thickness x smoking interaction ( 32117412) Chronotype ( 30696823) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Platelet distribution width ( 32888494) Red blood cell count ( 32888494) Red cell distribution width ( 32888494)
Novel Interacting Genes		2 novel interacting genes: RASGRP1 VTCN1
Interacting Genes		10 interacting genes: CTNNB1 ERG H3C1 NLGN3 SMAD3 TRIM24 UBE2D2 UBE2D3 UBE2E1 UBE2N
Entrez ID		51592
HPRD ID		10423
Ensembl ID		ENSG00000197323
Uniprot IDs		B3KN30 Q9UPN9
PDB IDs		3U5M 3U5N 3U5O 3U5P 5MR8
Enriched GO Terms of Interacting Partners?
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