MMP16

Description		matrix metallopeptidase 16
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GO Annotations	Cellular Component	Golgi Lumen Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Extracellular Matrix
	Molecular Function	Metalloendopeptidase Activity Enzyme Activator Activity Zinc Ion Binding Metalloaminopeptidase Activity
	Biological Process	Skeletal System Development Endochondral Ossification Proteolysis Protein Processing Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Chondrocyte Proliferation Embryonic Cranial Skeleton Morphogenesis Regulation Of Catalytic Activity Craniofacial Suture Morphogenesis
Pathways		Activation of Matrix Metalloproteinases
Drugs		Marimastat Batimastat
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bipolar disorder ( 31043756) Body mass index and cholesterol (psychopharmacological treatment) ( 22417934) Cerebral amyloid deposition (PET imaging) ( 26252872) Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903) Heel bone mineral density ( 30598549) Irritable mood ( 29500382) Migraine without aura ( 23793025) Refractive error ( 32231278) Schizophrenia ( 28991256 25056061 21926974 29483656 22688191 30285260 23974872) Sweet taste perception in obesity with metabolic syndrome ( 31005965)
Novel Interacting Genes		3 novel interacting genes: DECR1 DNAAF5 PIP4P2
Interacting Genes		2 interacting genes: KISS1 LRP1
Entrez ID		4325
HPRD ID		03776
Ensembl ID		ENSG00000156103
Uniprot IDs		P51512
PDB IDs		1RM8
Enriched GO Terms of Interacting Partners?
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