MAT1A

Description		methionine adenosyltransferase 1A
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GO Annotations	Cellular Component	Cytosol
	Molecular Function	Methionine Adenosyltransferase Activity Protein Binding ATP Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Sulfur Amino Acid Metabolic Process Selenium Compound Metabolic Process S-adenosylmethionine Biosynthetic Process One-carbon Metabolic Process Methionine Catabolic Process Methylation Protein Homotetramerization
Pathways		Methylation Sulfur amino acid metabolism Metabolism of ingested SeMet, Sec, MeSec into H2Se Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Drugs		Ademetionine 3-Oxiran-2ylalanine L-2-amino-4-methoxy-cis-but-3-enoic acid
Diseases		Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GWAS		Diabetic kidney disease ( 26305897)
Interacting Genes		1 interacting genes: MAT2A
Entrez ID		4143
HPRD ID		02013
Ensembl ID		ENSG00000151224
Uniprot IDs		Q00266
PDB IDs		2OBV 6SW5 6SW6
Enriched GO Terms of Interacting Partners?
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