PLA2G2E

Description		phospholipase A2 group IIE
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm
	Molecular Function	Phospholipase A2 Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipase A2 Activity Phospholipase A2 Activity (consuming 1,2-dipalmitoylphosphatidylcholine) Phospholipase A2 Activity Consuming 1,2-dioleoylphosphatidylethanolamine)
	Biological Process	Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Inflammatory Response Lipid Catabolic Process Low-density Lipoprotein Particle Remodeling Phosphatidylglycerol Acyl-chain Remodeling Phosphatidylinositol Acyl-chain Remodeling Phosphatidylserine Acyl-chain Remodeling Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Arachidonic Acid Secretion
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PS Acyl chain remodelling of PE Acyl chain remodelling of PI Acyl chain remodelling of PG Synthesis of PA
Drugs		Aminosalicylic acid 1,4-Butanediol N-Tridecanoic Acid 9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid Indolepropionic acid P-Anisic Acid Oxyphenbutazone Licofelone Nimesulide (R)-Atenolol (2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one Indoleacetic acid (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID 3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL Glycerin
Diseases
GWAS		group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471) Ulcerative colitis ( 19915572 20228799 19122664 23511034)
Interacting Genes		1 interacting genes: MALL
Entrez ID		30814
HPRD ID		07143
Ensembl ID		ENSG00000188784
Uniprot IDs		Q9NZK7
PDB IDs		5WZM 5WZO 5WZS 5WZT 5WZU 5WZV 5WZW 5Y5E 6KQU
Enriched GO Terms of Interacting Partners?
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