HCRTR2

Description		hypocretin receptor 2
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Synapse
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Neuropeptide Receptor Activity Orexin Receptor Activity Peptide Hormone Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Feeding Behavior Regulation Of Circadian Sleep/wake Cycle, Wakefulness Circadian Sleep/wake Cycle Process Regulation Of Cytosolic Calcium Ion Concentration
Pathways		Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events
Drugs		Suvorexant Lemborexant
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Chronotype ( 30696823 27494321) Excessive daytime sleepiness ( 27992416) Fasting glucose change (long-term) ( 31263163) HIV-1 control ( 20041166) Menarche (age at onset) ( 25231870) Morning person ( 30696823) Morning vs. evening chronotype ( 26835600 27494321) Severity of nausea and vomiting of pregnancy ( 29563502) Sleep duration (short sleep) ( 30846698) Sleep traits (multi-trait analysis) ( 27992416)
Novel Interacting Genes		1 novel interacting genes: TFAP2B
Interacting Genes		2 interacting genes: CD200 HCRT
Entrez ID		3062
HPRD ID		08374
Ensembl ID		ENSG00000137252
Uniprot IDs		O43614 S4X0W3
PDB IDs		4S0V 5WQC 5WS3 6TPG 6TPJ 6TPN
Enriched GO Terms of Interacting Partners?
Tagcloud ?