HCRTR1

Description		hypocretin receptor 1
Image
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Synapse
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Orexin Receptor Activity Peptide Hormone Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Chemical Synaptic Transmission Feeding Behavior Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of ERK1 And ERK2 Cascade
Pathways		Orexin and neuropeptides FF and QRFP bind to their respective receptors G alpha (q) signalling events
Drugs		Suvorexant Lemborexant
Diseases
GWAS		Asthma ( 31959851) Body mass index ( 26426971) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) General cognitive ability ( 29844566)
Novel Interacting Genes		3 novel interacting genes: ATP1B1 IFNGR2 PABPC4
Interacting Genes		4 interacting genes: ARRB1 ARRB2 CNR1 HCRT
Entrez ID		3061
HPRD ID		03863
Ensembl ID		ENSG00000121764
Uniprot IDs		A6NMV7 O43613
PDB IDs		4ZJ8 4ZJC 6TO7 6TOD 6TOS 6TOT 6TP3 6TP4 6TP6 6TQ4 6TQ6 6TQ7 6TQ9 6V9S
Enriched GO Terms of Interacting Partners?
Tagcloud ?