GLO1

Description		glyoxalase I
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Lactoylglutathione Lyase Activity Protein Binding Zinc Ion Binding
	Biological Process	Carbohydrate Metabolic Process Pyruvate Metabolic Process Regulation Of Transcription By RNA Polymerase II Glutathione Metabolic Process Methylglyoxal Metabolic Process Osteoclast Differentiation Negative Regulation Of Apoptotic Process
Pathways		Pyruvate metabolism
Drugs		Glutathione Indomethacin S-P-Nitrobenzyloxycarbonylglutathione S-(N-hydroxy-N-iodophenylcarbamoyl)glutathione Mercaptoethanol S-benzylglutathione S-Hexylglutathione methyl 4-(2,3-dihydroxy-5-methylphenoxy)-2-hydroxy-6-methylbenzoate
Diseases
GWAS		Blood protein levels ( 30072576) Major depressive disorder ( 29317602) Restless legs syndrome ( 29029846)
Interacting Genes		4 interacting genes: IKBKG MAP3K13 MEOX2 PJA1
Entrez ID		2739
HPRD ID		00730
Ensembl ID		ENSG00000124767
Uniprot IDs		Q04760 X5DNM4
PDB IDs		1BH5 1FRO 1QIN 1QIP 3VW9 3W0T 3W0U
Enriched GO Terms of Interacting Partners?
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