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GLA

Description galactosidase alpha
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Cytoplasm
  • Lysosome
  • Golgi Apparatus
  • Azurophil Granule Lumen
  • Lysosomal Lumen
  • Extracellular Exosome
Molecular Function
  • Catalytic Activity
  • Alpha-galactosidase Activity
  • Signaling Receptor Binding
  • Protein Binding
  • Hydrolase Activity
  • Galactosylgalactosylglucosylceramidase Activity
  • Protein Homodimerization Activity
  • Raffinose Alpha-galactosidase Activity
Biological Process
  • Glycosphingolipid Metabolic Process
  • Oligosaccharide Metabolic Process
  • Glycoside Catabolic Process
  • Neutrophil Degranulation
  • Negative Regulation Of Nitric Oxide Biosynthetic Process
  • Glycosylceramide Catabolic Process
  • Glycosphingolipid Catabolic Process
  • Negative Regulation Of Nitric-oxide Synthase Activity
Pathways
  • Glycosphingolipid metabolism
  • Neutrophil degranulation
Drugs
  • Migalastat
Diseases
  • Fabry disease
GWAS
Novel Interacting Genes 12 novel interacting genes: ANKRD30A CCR2 COL4A5 DUSP6 GPR17 GUCY2F HNRNPH2 MORF4L2 NAP1L3 NOSTRIN PDE6B PLP1
Interacting Genes 1 interacting genes: TERT
Entrez ID 2717
HPRD ID 02357
Ensembl ID ENSG00000102393
Uniprot IDs P06280 Q53Y83
PDB IDs 1R46 1R47 3GXN 3GXP 3GXT 3HG2 3HG3 3HG4 3HG5 3LX9 3LXA 3LXB 3LXC 3S5Y 3S5Z 3TV8 4NXS 6IBK 6IBM 6IBR 6IBT
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025