HIBCH

Description		3-hydroxyisobutyryl-CoA hydrolase
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	3-hydroxyisobutyryl-CoA Hydrolase Activity
	Biological Process	Valine Catabolic Process Branched-chain Amino Acid Catabolic Process
Pathways		Branched-chain amino acid catabolism
Drugs		Quercetin
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Blood protein levels ( 30072576) Daytime sleep phenotypes ( 27126917) Lung cancer (SNP x SNP interaction) ( 24325914) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolites ( 26352407)
Novel Interacting Genes		1 novel interacting genes: MFSD6
Interacting Genes
Entrez ID		26275
HPRD ID		11023
Ensembl ID		ENSG00000198130
Uniprot IDs		A0A140VJL0 Q6NVY1
PDB IDs		3BPT
Enriched GO Terms of Interacting Partners?
Tagcloud ?