TIAM2

Description		TIAM Rac1 associated GEF 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane Lamellipodium Filopodium Growth Cone Perikaryon Synapse Extracellular Exosome
	Molecular Function	GTPase Activator Activity
	Biological Process	G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Regulation Of Lipid Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Activation Of GTPase Activity
Pathways		NRAGE signals death through JNK Rho GTPase cycle PPARA activates gene expression G alpha (12/13) signalling events
Drugs
Diseases
GWAS		Accelerated cognitive decline after conversion of mild cognitive impairment to Alzheimer's disease (Alzhiemer's diagnosis trajectory interaction) ( 28560309) Asthma ( 31361310) Dimensional psychopathology (Arousal) ( 29496196) Dimensional psychopathology (Negative) ( 29496196) Heel bone mineral density ( 30598549) Lipoprotein (a) levels ( 26377243) Triiodothyronine levels and thyroxine levels ( 30843173)
Interacting Genes		9 interacting genes: ANXA7 DISC1 DNM2 H2AX PARD3 SH3GL2 TK1 TNIK UFD1
Entrez ID		26230
HPRD ID		05273
Ensembl ID		ENSG00000146426
Uniprot IDs		B3KW11 Q8IVF5
PDB IDs
Enriched GO Terms of Interacting Partners?
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