ABCA4

Description		ATP binding cassette subfamily A member 4
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Photoreceptor Disc Membrane
	Molecular Function	Transporter Activity Lipid Transporter Activity ATP Binding Phospholipid Transporter Activity ATPase Activity ATPase-coupled Transmembrane Transporter Activity Phosphatidylethanolamine Flippase Activity ATPase-coupled Intramembrane Lipid Transporter Activity Flippase Activity N-retinylidene-phosphatidylethanolamine Flippase Activity
	Biological Process	Retinoid Metabolic Process Phospholipid Transfer To Membrane Lipid Transport Visual Perception Phototransduction, Visible Light Phospholipid Translocation Photoreceptor Cell Maintenance Transmembrane Transport
Pathways		Retinoid cycle disease events The canonical retinoid cycle in rods (twilight vision) The canonical retinoid cycle in rods (twilight vision) ABC-family proteins mediated transport
Drugs
Diseases		Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA) Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD) Stargardt disease (STGD); Fundus flavimaculatus Retinitis pigmentosa (RP)
GWAS		D-dimer levels ( 21502573) Dialysis-related mortality ( 21546767) Nonsyndromic cleft lip with cleft palate ( 28232668) Palmitoleic acid (16:1n-7) levels ( 23362303) Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: ATP1A3
Interacting Genes		1 interacting genes: CNGB1
Entrez ID		24
HPRD ID		03408
Ensembl ID		ENSG00000198691
Uniprot IDs		P78363 Q6AI28
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?