COTL1

Description		coactosin like F-actin binding protein 1
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GO Annotations	Cellular Component	Extracellular Region Nucleus Cytosol Actin Filament Plasma Membrane Cortical Actin Cytoskeleton Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Actin Binding Protein Binding Enzyme Binding Actin Filament Binding
	Biological Process	Biological_process Regulation Of Actin Filament Polymerization Neutrophil Degranulation Defense Response To Fungus
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) Cleft lip with or without cleft palate (maternal periconceptional vitamin use interaction) ( 29535761) Cocaine dependence ( 31212010) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Heel bone mineral density ( 30598549) Macular thickness ( 30535121)
Novel Interacting Genes		1 novel interacting genes: BBS5
Interacting Genes		6 interacting genes: ACTA1 ACTB ACTG1 ALOX5 PDE6H TERF2IP
Entrez ID		23406
HPRD ID		09482
Ensembl ID		ENSG00000103187
Uniprot IDs		A0A384MTY2 Q14019
PDB IDs		1T2L 1T3X 1T3Y 1TMW 1VFQ 1WNJ
Enriched GO Terms of Interacting Partners?
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