KANK1

Description		KN motif and ankyrin repeat domains 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Ruffle Membrane
	Molecular Function	Protein Binding Beta-catenin Binding
	Biological Process	Cell Population Proliferation Negative Regulation Of Neuron Projection Development Actin Cytoskeleton Organization Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Migration Negative Regulation Of Actin Filament Polymerization Regulation Of Rho Protein Signal Transduction Negative Regulation Of Rho Protein Signal Transduction Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Wound Healing Glomerular Visceral Epithelial Cell Migration Negative Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Ruffle Assembly Regulation Of Establishment Of Cell Polarity Negative Regulation Of Lamellipodium Morphogenesis
Pathways		Estrogen-dependent gene expression Signaling by membrane-tethered fusions of PDGFRA or PDGFRB
Drugs
Diseases		Cerebral palsy
GWAS		Bone mineral density (femoral neck) in inflammatory bowel disease ( 29603369) Eye morphology ( 29921221) Fasting plasma glucose ( 25187374) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Night sleep phenotypes ( 27126917) Post bronchodilator FEV1/FVC ratio ( 26634245) Proinsulin levels (early-phase conversion) ( 23263489) Serum bilirubin levels in metabolic syndrome ( 30621171) Systolic blood pressure ( 30224653) Uterine fibroids ( 30194396)
Interacting Genes		9 interacting genes: AKT1 BAIAP2 PPP1CA YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID		23189
HPRD ID		09651
Ensembl ID		ENSG00000107104
Uniprot IDs		Q14678
PDB IDs		5YBJ 5YBU
Enriched GO Terms of Interacting Partners?
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