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CASC3

Description CASC3 exon junction complex subunit
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytosol
  • Cytoplasmic Stress Granule
  • Nuclear Speck
  • Dendrite
  • Nuclear Membrane
  • Exon-exon Junction Complex
  • Perinuclear Region Of Cytoplasm
  • U2-type Catalytic Step 1 Spliceosome
Molecular Function
  • RNA Binding
  • Protein Binding
  • Enzyme Binding
  • Ubiquitin Protein Ligase Binding
  • Identical Protein Binding
Biological Process
  • Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
  • MRNA Splicing, Via Spliceosome
  • RNA Export From Nucleus
  • MRNA Export From Nucleus
  • Regulation Of Translation
  • Intracellular MRNA Localization
  • MRNA 3'-end Processing
Pathways
  • Transport of Mature mRNA derived from an Intron-Containing Transcript
  • mRNA Splicing - Major Pathway
  • mRNA 3'-end processing
  • RNA Polymerase II Transcription Termination
  • Regulation of expression of SLITs and ROBOs
  • Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
  • Asthma ( 31619474)
  • Household income ( 31844048)
Novel Interacting Genes 1 novel interacting genes: STARD3
Interacting Genes 16 interacting genes: AKT1 APC CASP8 CDK6 CDKN2A EIF4A3 ESR2 FGFR4 GRB2 KRTAP6-2 MIR128-1 NBN PHB PTPN1 PTPRJ STAU1
Entrez ID 22794
HPRD ID 16225
Ensembl ID ENSG00000108349
Uniprot IDs O15234
PDB IDs 2HYI 2J0Q 2J0S 2J0U 2XB2 3EX7 5XJC 5YZG 6ICZ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025