FCER1A

Description		Fc fragment of IgE receptor Ia
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding IgE Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Regulation Of Immune Response
Pathways		Fc epsilon receptor (FCERI) signaling Fc epsilon receptor (FCERI) signaling Role of LAT2/NTAL/LAB on calcium mobilization Role of LAT2/NTAL/LAB on calcium mobilization FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization FCERI mediated NF-kB activation
Drugs		Omalizumab Benzylpenicilloyl polylysine TNX-901
Diseases
GWAS		C-reactive protein ( 22939635) IgE levels ( 18846228 22075330) Obesity-related traits ( 23251661) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Select biomarker traits ( 17903293) White blood cell count ( 27863252)
Novel Interacting Genes		1 novel interacting genes: FCGR2A
Interacting Genes		6 interacting genes: FCER1G ITIH2 LMNA MESD MS4A2 PDHB
Entrez ID		2205
HPRD ID		00917
Ensembl ID		ENSG00000179639
Uniprot IDs		P12319
PDB IDs		1ALS 1ALT 1F2Q 1F6A 1J86 1J87 1J88 1J89 1RPQ 2Y7Q
Enriched GO Terms of Interacting Partners?
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