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ACSL1
Description
acyl-CoA synthetase long chain family member 1
Image
No pdb structure
GO Annotations
Cellular Component
Mitochondrion
Mitochondrial Outer Membrane
Peroxisomal Membrane
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Integral Component Of Membrane
Molecular Function
Long-chain Fatty Acid-CoA Ligase Activity
ATP Binding
Arachidonate-CoA Ligase Activity
Phytanate-CoA Ligase Activity
Oleoyl-CoA Ligase Activity
Biological Process
Very Long-chain Fatty Acid Metabolic Process
Long-chain Fatty Acid Metabolic Process
Response To Nutrient
Lipid Biosynthetic Process
Positive Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane
Response To Organic Cyclic Compound
Fatty Acid Transport
Regulation Of Lipid Metabolic Process
Triglyceride Biosynthetic Process
Adiponectin-activated Signaling Pathway
Response To Oleic Acid
Long-chain Fatty-acyl-CoA Biosynthetic Process
Alpha-linolenic Acid Metabolic Process
Xenobiotic Catabolic Process
Response To Drug
Linoleic Acid Metabolic Process
Long-chain Fatty Acid Import Into Cell
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Cold-induced Thermogenesis
Pathways
PPARA activates gene expression
Linoleic acid (LA) metabolism
alpha-linolenic acid (ALA) metabolism
Synthesis of very long-chain fatty acyl-CoAs
Drugs
Adenosine phosphate
ATP
Diseases
GWAS
Fulminant type 1 diabetes (
30552108
)
Mean platelet volume (
32888494
)
Neuroblastoma or malignant cutaneous melanoma (
31605138
)
Night sleep phenotypes (
27126917
)
Type 2 diabetes (
28566273
30054458
30297969
)
Interacting Genes
1 interacting genes:
NR3C2
Entrez ID
2180
HPRD ID
01068
Ensembl ID
ENSG00000151726
Uniprot IDs
A8K9T3
B4E0R0
B7Z3Z9
E7EPM6
P33121
PDB IDs
Enriched GO Terms of Interacting Partners
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