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DHFR2

Description dihydrofolate reductase 2
Image No pdb structure
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Inner Membrane
  • Mitochondrial Matrix
Molecular Function
  • MRNA Binding
  • Dihydrofolate Reductase Activity
  • NADP Binding
Biological Process
  • Glycine Biosynthetic Process
  • One-carbon Metabolic Process
  • Thymidine Biosynthetic Process
  • Dihydrofolate Metabolic Process
  • Tetrahydrofolate Metabolic Process
  • Tetrahydrofolate Biosynthetic Process
  • Folic Acid Metabolic Process
Pathways
  • Metabolism of folate and pterines
Drugs
  • 5-Chloryl-2,4,6-quinazolinetriamine
  • 5-[4-Tert-Butylphenylsulfanyl]-2,4-Quinazolinediamine
  • 5-(4-Morpholin-4-Yl-Phenylsulfanyl)-2,4-Quinazolinediamine
  • 5-(4-Methoxyphenoxy)-2,4-Quinazolinediamine
  • 5-Phenylsulfanyl-2,4-Quinazolinediamine
  • 5-[(4-Methylphenyl)Sulfanyl]-2,4-Quinazolinediamine
  • 7-(1-ETHYL-PROPYL)-7H-PYRROLO-[3,2-F]QUINAZOLINE-1,3-DIAMINE
  • 7-[2-METHOXY-1-(METHOXYMETHYL)ETHYL]-7H-PYRROLO[3,2-F] QUINAZOLINE-1,3-DIAMINE
  • Epigallocatechin gallate
Diseases
GWAS
Novel Interacting Genes 1 novel interacting genes: ARL13B
Interacting Genes 1 interacting genes: TINF2
Entrez ID 200895
HPRD ID 11246
Ensembl ID ENSG00000178700
Uniprot IDs Q86XF0
PDB IDs
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025