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EGR2
Description
early growth response 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Intracellular Membrane-bounded Organelle
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Sequence-specific DNA Binding
Metal Ion Binding
SUMO Ligase Activity
HMG Box Domain Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Regulation Of Transcription By RNA Polymerase II
Protein Export From Nucleus
Brain Development
Peripheral Nervous System Development
Learning Or Memory
Rhythmic Behavior
Motor Neuron Axon Guidance
Gene Expression
Schwann Cell Differentiation
Positive Regulation Of Schwann Cell Differentiation
Protein Sumoylation
Facial Nerve Structural Organization
Rhombomere 3 Structural Organization
Rhombomere 3 Formation
Rhombomere 5 Structural Organization
Rhombomere 5 Formation
Regulation Of Ossification
Positive Regulation Of Myelination
Response To Insulin
Brain Segmentation
Skeletal Muscle Cell Differentiation
Myelination
Fat Cell Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Neuronal Synaptic Plasticity
Cellular Response To Organic Substance
Pathways
Transcriptional regulation of white adipocyte differentiation
Activation of anterior HOX genes in hindbrain development during early embryogenesis
NGF-stimulated transcription
NGF-stimulated transcription
EGR2 and SOX10-mediated initiation of Schwann cell myelination
EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS
Adventurousness (
30643258
)
Alopecia areata (
25608926
)
Atopic dermatitis (
23042114
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Ewing sarcoma (
22327514
)
HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) (
30698716
)
LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) (
30698716
)
LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) (
30698716
)
Monocyte percentage of white cells (
32888494
)
Selective IgA deficiency (
27723758
)
Temperament (
22832960
)
Triglyceride levels (
30698716
)
Triglyceride levels in current drinkers (
30698716
)
Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) (
30698716
)
Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) (
30698716
)
Vogt-Koyanagi-Harada syndrome (
25108386
)
Novel Interacting Genes
1 novel interacting genes:
KCTD17
Interacting Genes
20 interacting genes:
ACP5
BPGM
DNMT3L
GOLGA2
HCFC1
JPT2
MCRS1
MED31
NAB2
NDUFS2
NFATC1
PDE4DIP
RBM15B
RIMKLB
RPL7L1
SOX10
SOX8
SRA1
UBE2I
WWP2
Entrez ID
1959
HPRD ID
00551
Ensembl ID
ENSG00000122877
Uniprot IDs
P11161
PDB IDs
Enriched GO Terms of Interacting Partners
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