CYP2C18

Description		cytochrome P450 family 2 subfamily C member 18
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GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Monooxygenase Activity Iron Ion Binding Arachidonic Acid Epoxygenase Activity Steroid Hydroxylase Activity Retinoic Acid 4-hydroxylase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, Reduced Flavin Or Flavoprotein As One Donor, And Incorporation Of One Atom Of Oxygen Oxygen Binding Heme Binding Aromatase Activity
	Biological Process	Organic Acid Metabolic Process Xenobiotic Metabolic Process Epoxygenase P450 Pathway Retinoic Acid Metabolic Process Exogenous Drug Catabolic Process
Pathways		Xenobiotics
Drugs		N,4-Dimethyl-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide
Diseases
GWAS		Acenocoumarol maintenance dosage ( 19578179) Clopidogrel active metabolite levels ( 28207573) Common carotid intima-media thickness in HIV negative individuals ( 29206233) Plasma clozapine-norclozapine ratio in treatment-resistant schizophrenia ( 30922102) Red cell distribution width ( 32888494) Response to clopidogrel therapy ( 28207573 19706858) Serum metabolite levels ( 23093944) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Warfarin maintenance dose ( 23755828) Warfarin maintenance dose (adjusted for clinical factors) ( 28686080)
Novel Interacting Genes		1 novel interacting genes: KMT2E
Interacting Genes		5 interacting genes: A2M APOE ECSIT PSEN1 SDC2
Entrez ID		1562
HPRD ID		03085
Ensembl ID		ENSG00000108242
Uniprot IDs		P33260 Q7Z348
PDB IDs		2CIK 2H6P
Enriched GO Terms of Interacting Partners?
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