TTBK2

Description		tau tubulin kinase 2
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GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Centriole Cytosol Ciliary Transition Zone Ciliary Basal Body
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinesin Binding Tau Protein Binding Tau-protein Kinase Activity Microtubule Plus-end Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity
	Biological Process	Microtubule Cytoskeleton Organization Negative Regulation Of Microtubule Depolymerization Smoothened Signaling Pathway Peptidyl-serine Phosphorylation Cerebellum Development Cerebellar Granular Layer Development Cerebellar Granule Cell Precursor Tangential Migration Regulation Of Cell Migration Cilium Assembly Ciliary Basal Body-plasma Membrane Docking Negative Regulation Of Protein Localization To Microtubule Negative Regulation Of Microtubule Binding
Pathways		Anchoring of the basal body to the plasma membrane
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bipolar disorder ( 31043756) Hematocrit ( 32888494) MGMT methylation in smokers ( 26183928)
Novel Interacting Genes		1 novel interacting genes: STARD9
Interacting Genes		1 interacting genes: KLHL12
Entrez ID		146057
HPRD ID		10288
Ensembl ID		ENSG00000128881
Uniprot IDs		Q6IQ55 Q8IWY7
PDB IDs		6U0K 6VRF
Enriched GO Terms of Interacting Partners?
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