COL11A2

Description		collagen type XI alpha 2 chain
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Trimer Collagen Type XI Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength Protein-macromolecule Adaptor Activity Metal Ion Binding
	Biological Process	Skeletal System Development Sensory Perception Of Sound Extracellular Matrix Organization Collagen Fibril Organization Cartilage Development Roof Of Mouth Development Soft Palate Development
Pathways		Collagen degradation Collagen degradation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Non-integrin membrane-ECM interactions MET activates PTK2 signaling Collagen chain trimerization
Drugs
Diseases		Ossification of the posterior longitudinal ligament of spine (OPLL) Deafness, autosomal dominant Type XI collagenopathies, including: Stickler syndrome type 2; Stickler syndrome type 3; Otospondylomegaepiphyseal dysplasia (OSMED); Marshall syndrome; Weissenbacher-Zweymuller syndrome Deafness, autosomal recessive
GWAS		Antineutrophil cytoplasmic antibody-associated vasculitis ( 22808956) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Blood protein levels ( 29875488) Height ( 31217584) Lung cancer ( 28604730) Rosacea symptom severity ( 29771307) SjÃ¶gren's syndrome ( 24097066) Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781) Wegener's granulomatosis ( 23740775)
Novel Interacting Genes		1 novel interacting genes: DAXX
Interacting Genes		3 interacting genes: ANXA7 PIN1 TK1
Entrez ID		1302
HPRD ID		00376
Ensembl ID		ENSG00000204248
Uniprot IDs		A0A0C4DFS1 H0YIS1 P13942 Q4VXY6
PDB IDs
Enriched GO Terms of Interacting Partners?
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