ADH1C

Description		alcohol dehydrogenase 1C (class I), gamma polypeptide
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	Alcohol Dehydrogenase (NAD+) Activity Alcohol Dehydrogenase Activity, Zinc-dependent Retinol Dehydrogenase Activity Zinc Ion Binding
	Biological Process	Ethanol Oxidation Retinol Metabolic Process Retinoic Acid Metabolic Process
Pathways		RA biosynthesis pathway Ethanol oxidation
Drugs		NADH Fomepizole 2,3,4,5,6-Pentafluorobenzyl Alcohol N-1-methylheptylformamide 2-Ethoxyethanol Cholic Acid 4-Iodopyrazole Pyrazole Para-Bromobenzyl Alcohol 3-Butylthiolane 1-Oxide 5-beta-D-ribofuranosylnicotinamide adenine dinucleotide (R)-N-(1-Methyl-Hexyl)-Formamide Trifluoroethanol Cyclohexylformamide Cpad N-Formylpiperidine 2,3-Difluorobenzyl Alcohol 2,4-Difluorobenzyl Alcohol 2,4-Difluoro-1-(Hydroxymethyl)Benzene
Diseases
GWAS		Alcohol consumption ( 28937693 31358974) Alcohol consumption (drinks per week) ( 30643258) Alcohol consumption in current drinkers ( 28937693) Alcohol consumption over the past year ( 29058377) Alcohol dependence ( 24166409 23456092 28714907 22004471) Alcohol use disorder ( 30940813) Alcohol use disorder (consumption score) ( 30940813) Alcohol use disorder (total score) ( 30336701) Bitter alcoholic beverage consumption ( 31046077) Cerebrospinal fluid clusterin levels ( 26545630) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Hematocrit ( 32888494) Lung cancer ( 28604730) Oral cavity and pharyngeal cancer ( 21437268 27749845) Regular attendance at a pub or social club ( 29970889) Total cholesterol levels ( 30275531)
Novel Interacting Genes		1 novel interacting genes: PKD2
Interacting Genes
Entrez ID		126
HPRD ID		00066
Ensembl ID		ENSG00000248144
Uniprot IDs		P00326
PDB IDs		1DDA 1HT0 1U3W
Enriched GO Terms of Interacting Partners?
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