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CCR6
Description
C-C motif chemokine receptor 6
Image
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
External Side Of Plasma Membrane
Cell Surface
Sperm Flagellum
Sperm Midpiece
Sperm Principal Piece
Sperm Plasma Membrane
Molecular Function
Chemokine Receptor Activity
Protein Binding
C-C Chemokine Receptor Activity
C-C Chemokine Binding
Signaling Receptor Activity
Biological Process
Dendritic Cell Chemotaxis
Leukocyte Migration Involved In Inflammatory Response
Chemotaxis
Immune Response
Humoral Immune Response
Cellular Defense Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Positive Regulation Of Epithelial Cell Migration
Calcium-mediated Signaling
Isotype Switching To IgA Isotypes
Cell Chemotaxis
Positive Regulation Of Flagellated Sperm Motility Involved In Capacitation
Chemokine-mediated Signaling Pathway
Lymphocyte Migration
T Cell Migration
Thymocyte Migration
DN2 Thymocyte Differentiation
DN3 Thymocyte Differentiation
Regulation Of T Cell Migration
Positive Regulation Of Dendritic Cell Chemotaxis
Pathways
Beta defensins
Chemokine receptors bind chemokines
G alpha (i) signalling events
Drugs
Diseases
GWAS
Albumin-globulin ratio (
29403010
)
Autoimmune thyroid diseases (Graves disease or Hashimoto's thyroiditis) (
22922229
)
Basal cell carcinoma (
31174203
)
Crohn's disease (
18587394
28067908
20570966
21102463
23850713
)
Graves' disease (
22922229
)
Inflammatory bowel disease (
27569725
28067908
23128233
)
Keratinocyte cancer (MTAG) (
31174203
)
Lung cancer (
28604730
)
Primary biliary cholangitis (
28425483
)
Response to zileuton treatment in asthma (FEV1 change interaction) (
26031901
)
Rheumatoid arthritis (
30423114
24782177
23143596
24390342
20453841
20453842
)
Rheumatoid arthritis (ACPA-positive) (
23143596
24532676
)
Social autistic-like traits (
24133439
)
Triglycerides (
24886709
)
Vitiligo (
20526339
27723757
)
Novel Interacting Genes
6 novel interacting genes:
AASS
AFDN
EIF4A3
MARK1
RBM14
ZNF92
Interacting Genes
5 interacting genes:
CCL20
DEFB1
DEFB103B
DEFB4A
QSOX1
Entrez ID
1235
HPRD ID
03498
Ensembl ID
ENSG00000112486
Uniprot IDs
P51684
PDB IDs
6WWZ
Enriched GO Terms of Interacting Partners
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