NEDD1

Description		NEDD1 gamma-tubulin ring complex targeting factor
Image		No pdb structure
GO Annotations	Cellular Component	Pericentriolar Material Spindle Pole Nucleoplasm Centrosome Centriole Cytosol Plasma Membrane Ciliary Basal Body Apical Part Of Cell
	Molecular Function	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Division Protein Localization To Centrosome Ciliary Basal Body-plasma Membrane Docking
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Autism ( 24189344) Breast size ( 22747683) Frontotemporal dementia ( 29724592) Frontotemporal dementia with GRN mutation ( 29724592) Manganese levels ( 26025379)
Interacting Genes		3 interacting genes: EP300 FBLN1 RND1
Entrez ID		121441
HPRD ID		02655
Ensembl ID		ENSG00000139350
Uniprot IDs		A0A024RBE5 A8K1Z3 Q8NHV4
PDB IDs
Enriched GO Terms of Interacting Partners?
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