CHRNA2

Description		cholinergic receptor nicotinic alpha 2 subunit
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Acetylcholine-gated Channel Complex Integral Component Of Membrane Neuron Projection Synapse Postsynaptic Membrane
	Molecular Function	Acetylcholine Receptor Activity Acetylcholine-gated Cation-selective Channel Activity Neurotransmitter Receptor Activity
	Biological Process	Ion Transport Signal Transduction Chemical Synaptic Transmission Synaptic Transmission, Cholinergic Ion Transmembrane Transport Response To Nicotine Regulation Of Membrane Potential Nervous System Process Excitatory Postsynaptic Potential
Pathways		Highly calcium permeable postsynaptic nicotinic acetylcholine receptors Highly calcium permeable nicotinic acetylcholine receptors
Drugs		Nicotine Butabarbital Carbamoylcholine Metocurine iodide Fluoxetine Gallamine triethiodide Dextromethorphan Cisatracurium Mecamylamine Procaine Rocuronium Atracurium besylate Ethanol Doxacurium Tubocurarine Mivacurium Decamethonium Metocurine Pancuronium Pipecuronium Vecuronium RPI-78M Epibatidine Hexamethonium
Diseases		Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE); Nocturnal frontal lobe epilepsy (NFLE)
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Autism spectrum disorder or schizophrenia ( 28540026) Cannabis use disorder ( 31209380) Lung cancer ( 28604730) Response to zileuton treatment in asthma (FEV1 change interaction) ( 26031901) Schizophrenia ( 29483656)
Interacting Genes		2 interacting genes: CHRNB2 CHRNB4
Entrez ID		1135
HPRD ID		00332
Ensembl ID		ENSG00000120903
Uniprot IDs		Q15822
PDB IDs		5FJV
Enriched GO Terms of Interacting Partners?
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