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CTSC
Description
cathepsin C
Image
GO Annotations
Cellular Component
Golgi Membrane
Extracellular Region
Extracellular Space
Nucleoplasm
Lysosome
Endoplasmic Reticulum Lumen
Centrosome
Membrane
COPII-coated ER To Golgi Transport Vesicle
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Azurophil Granule Lumen
Intracellular Membrane-bounded Organelle
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
Cysteine-type Endopeptidase Activity
Serine-type Endopeptidase Activity
Protein Binding
Cysteine-type Peptidase Activity
Dipeptidyl-peptidase Activity
Peptidase Activator Activity Involved In Apoptotic Process
Phosphatase Binding
Chloride Ion Binding
Identical Protein Binding
Protein Self-association
Chaperone Binding
Biological Process
T Cell Mediated Cytotoxicity
Proteolysis
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Apoptotic Process
Immune Response
Aging
Response To Organic Substance
Negative Regulation Of Myelination
Neutrophil Degranulation
COPII Vesicle Coating
Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Microglial Cell Activation
Positive Regulation Of Apoptotic Signaling Pathway
Pathways
COPII-mediated vesicle transport
MHC class II antigen presentation
Cargo concentration in the ER
Neutrophil degranulation
Drugs
Diseases
Papillon-Lefevre syndrome
Haim-Munk syndrome
GWAS
Basophil percentage of white cells (
32888494
)
Blood protein levels (
30072576
)
Neurological blood protein biomarker levels (
31320639
)
Interacting Genes
3 interacting genes:
CAPN1
CTSL
XRN2
Entrez ID
1075
HPRD ID
03841
Ensembl ID
ENSG00000109861
Uniprot IDs
P53634
PDB IDs
1K3B
2DJF
2DJG
3PDF
4CDC
4CDD
4CDE
4CDF
4OEL
4OEM
Enriched GO Terms of Interacting Partners
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