ABCA8

Description		ATP binding cassette subfamily A member 8
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Lipid Transporter Activity ATP Binding ABC-type Xenobiotic Transporter Activity ATPase-coupled Transmembrane Transporter Activity ABC-type Transporter Activity
	Biological Process	Sphingomyelin Biosynthetic Process Lipid Transport Regulation Of Cholesterol Efflux Positive Regulation Of Cholesterol Efflux Cholesterol Transport Cholesterol Efflux Xenobiotic Transport Transmembrane Transport
Pathways		ABC-family proteins mediated transport
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Cholesterol, total ( 26582766) Coronary artery disease ( 29212778) group IIA secretory phospholipase A2 levels in individuals with elevated hsCRP ( 31070471) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 32203549 28334899) Late-onset Alzheimer's disease ( 27770636) LDL cholesterol ( 25961943) Phosphorus levels ( 29403010) Soluble VCAM-1 levels ( 31217265) T-Cell Immunoglobulin and Mucin domain 1 levels ( 32460577)
Novel Interacting Genes		1 novel interacting genes: BACE2
Interacting Genes
Entrez ID		10351
HPRD ID		09790
Ensembl ID		ENSG00000141338
Uniprot IDs		A0A024R8L6 A0A0A0MSU4 O94911
PDB IDs
Enriched GO Terms of Interacting Partners?
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