TOX and DMRTB1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TOX	DMRTB1
Description		thymocyte selection associated high mobility group box	DMRT like family B with proline rich C-terminal 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus
	Molecular Function	Protein Binding Chromatin DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Natural Killer Cell Differentiation CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Lineage Commitment NK T Cell Lineage Commitment Leukocyte Differentiation Chromatin Organization Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Cerebral Cortex Neuron Differentiation Positive Regulation Of Natural Killer Cell Differentiation CD4-positive, Alpha-beta T Cell Lineage Commitment CD8-positive, Alpha-beta T Cell Lineage Commitment Lymph Node Development Peyer's Patch Development Positive Regulation Of DNA Demethylation Regulation Of Positive Thymic T Cell Selection Positive Regulation Of Neural Precursor Cell Proliferation	Regulation Of Transcription By RNA Polymerase II Germ Cell Development Sex Differentiation
Pathways
Drugs
Diseases
GWAS		Chronotype ( 30696823) Cognitive performance ( 19734545) Height ( 31562340) High myopia ( 31816047) Hyperopia ( 25233373) Mercury levels ( 26025379) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Myopia ( 27182965 25233373) Oily fish consumption ( 32066663) Parental longevity (father's attained age) ( 29227965) Pork consumption ( 32066663) Psychological resilience (outcome-based) ( 31081985) Refractive astigmatism ( 25367360) Refractive error ( 23396134 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Superior temporal sulcus banks volume ( 31530798) Systolic blood pressure ( 30224653) Type 1 diabetes ( 34012112) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Cerebrospinal fluid AB1-42 levels ( 28247064) Response to statin therapy ( 20339536)
Interacting Genes		6 interacting genes: BANP DMRTB1 GRAP KRTAP12-1 KRTAP26-1 ZDHHC17	40 interacting genes: C1orf94 CCND3 CDKN2D CTBP1 CTBP2 EWSR1 EXOSC1 EXOSC5 EYA2 FXR2 HNRNPUL1 IL16 INCA1 KRTAP19-5 KRTAP19-6 KRTAP21-2 KRTAP8-1 LENG8 NCKIPSD NEDD9 NIF3L1 PARD6G PEF1 PKP2 PRMT2 QKI RAMAC RBFOX1 RBFOX2 RBM14 RBPMS RPA2 SH3RF1 SLAIN1 SORBS3 TENT5A TLE5 TOX TSG101 VASP
Entrez ID		9760	63948
HPRD ID		12113	16828
Ensembl ID		ENSG00000198846	ENSG00000143006
Uniprot IDs		O94900	I6L9A0 Q96MA1
PDB IDs
Enriched GO Terms of Interacting Partners?
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