TOX and GRAP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TOX	GRAP
Description		thymocyte selection associated high mobility group box	GRB2 related adaptor protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Cytosol Membrane Presynapse
	Molecular Function	Protein Binding Chromatin DNA Binding	Protein Binding
	Biological Process	Natural Killer Cell Differentiation CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Lineage Commitment NK T Cell Lineage Commitment Leukocyte Differentiation Chromatin Organization Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Cerebral Cortex Neuron Differentiation Positive Regulation Of Natural Killer Cell Differentiation CD4-positive, Alpha-beta T Cell Lineage Commitment CD8-positive, Alpha-beta T Cell Lineage Commitment Lymph Node Development Peyer's Patch Development Positive Regulation Of DNA Demethylation Regulation Of Positive Thymic T Cell Selection Positive Regulation Of Neural Precursor Cell Proliferation	Ras Protein Signal Transduction Cell-cell Signaling Sensory Perception Of Sound
Pathways			Signaling by SCF-KIT
Drugs
Diseases
GWAS		Chronotype ( 30696823) Cognitive performance ( 19734545) Height ( 31562340) High myopia ( 31816047) Hyperopia ( 25233373) Mercury levels ( 26025379) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Myopia ( 27182965 25233373) Oily fish consumption ( 32066663) Parental longevity (father's attained age) ( 29227965) Pork consumption ( 32066663) Psychological resilience (outcome-based) ( 31081985) Refractive astigmatism ( 25367360) Refractive error ( 23396134 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Superior temporal sulcus banks volume ( 31530798) Systolic blood pressure ( 30224653) Type 1 diabetes ( 34012112) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Copper levels ( 26025379)
Interacting Genes		6 interacting genes: BANP DMRTB1 GRAP KRTAP12-1 KRTAP26-1 ZDHHC17	19 interacting genes: ARHGAP32 DPPA4 EPOR FASLG FYN GAB2 KHDRBS1 KIT LAT LCK PLCG1 PRRG4 RAI1 RBPMS REL SHC1 SOS1 TOX TRIM21
Entrez ID		9760	10750
HPRD ID		12113	05062
Ensembl ID		ENSG00000198846	ENSG00000154016
Uniprot IDs		O94900	I3L2P9 Q13588
PDB IDs
Enriched GO Terms of Interacting Partners?
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