TOX and KRTAP12-1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		TOX	KRTAP12-1
Description		thymocyte selection associated high mobility group box	keratin associated protein 12-1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytosol Keratin Filament
	Molecular Function	Protein Binding Chromatin DNA Binding	Protein Binding
	Biological Process	Natural Killer Cell Differentiation CD4-positive, CD25-positive, Alpha-beta Regulatory T Cell Lineage Commitment NK T Cell Lineage Commitment Leukocyte Differentiation Chromatin Organization Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Cerebral Cortex Neuron Differentiation Positive Regulation Of Natural Killer Cell Differentiation CD4-positive, Alpha-beta T Cell Lineage Commitment CD8-positive, Alpha-beta T Cell Lineage Commitment Lymph Node Development Peyer's Patch Development Positive Regulation Of DNA Demethylation Regulation Of Positive Thymic T Cell Selection Positive Regulation Of Neural Precursor Cell Proliferation
Pathways			Keratinization
Drugs
Diseases
GWAS		Chronotype ( 30696823) Cognitive performance ( 19734545) Height ( 31562340) High myopia ( 31816047) Hyperopia ( 25233373) Mercury levels ( 26025379) Modified Stumvoll Insulin Sensitivity Index (BMI interaction) ( 27416945) Myopia ( 27182965 25233373) Oily fish consumption ( 32066663) Parental longevity (father's attained age) ( 29227965) Pork consumption ( 32066663) Psychological resilience (outcome-based) ( 31081985) Refractive astigmatism ( 25367360) Refractive error ( 23396134 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Superior temporal sulcus banks volume ( 31530798) Systolic blood pressure ( 30224653) Type 1 diabetes ( 34012112) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		6 interacting genes: BANP DMRTB1 GRAP KRTAP12-1 KRTAP26-1 ZDHHC17	60 interacting genes: CATSPER1 CHRD CYSRT1 DHRS1 ENKD1 FHL3 GATA3 GPRIN2 GRN HOXA1 HOXC8 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-2 KRTAP12-3 KRTAP15-1 KRTAP26-1 KRTAP3-2 KRTAP4-4 KRTAP4-5 KRTAP5-6 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1E LCE1F LCE2A LCE2B LCE2C MEOX2 MGAT5B NBPF19 NEU4 NOTCH2NLA OTX1 PDIA2 PDIA4 PEF1 POU2AF1 POU4F2 PRR35 RBPMS SMCP TOX TRIP13 UBQLN2 VGLL3 ZIC1
Entrez ID		9760	353332
HPRD ID		12113	11197
Ensembl ID		ENSG00000198846	ENSG00000187175
Uniprot IDs		O94900	P59990
PDB IDs
Enriched GO Terms of Interacting Partners?
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