PICK1 and HSF2BP

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PICK1	HSF2BP
Description		protein interacting with PRKCA 1	heat shock transcription factor 2 binding protein
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Plasma Membrane Synaptic Vesicle Postsynaptic Density Endocytic Vesicle Membrane Trans-Golgi Network Membrane Presynaptic Membrane Neuron Projection Synapse Perinuclear Region Of Cytoplasm Postsynaptic Early Endosome	Chromosome Cytosol
	Molecular Function	G Protein-coupled Receptor Binding Protein Kinase C Binding Signaling Receptor Binding Protein Binding Phospholipid Binding Protein C-terminus Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Metal Ion Binding Actin Filament Binding Arp2/3 Complex Binding Membrane Curvature Sensor Activity	Protein Binding
	Biological Process	Positive Regulation Of Receptor Internalization Protein Phosphorylation Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Monoamine Transport Glial Cell Development Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Response To Decreased Oxygen Levels Cellular Response To Glucose Starvation DNA Methylation Involved In Embryo Development DNA Methylation Involved In Gamete Generation Receptor Clustering Neuronal Ion Channel Clustering Regulation Of Insulin Secretion Long-term Synaptic Depression Dendritic Spine Organization Dendritic Spine Maintenance	Transcription By RNA Polymerase II Male Meiosis I Female Meiosis I Spermatogenesis Double-strand Break Repair Involved In Meiotic Recombination
Pathways		Cell surface interactions at the vascular wall Trafficking of GluR2-containing AMPA receptors
Drugs
Diseases
GWAS		Body fat percentage ( 26833246) Brain morphology (MOSTest) ( 32665545) Mean platelet volume ( 32888494)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Coronary artery disease ( 29212778) Eosinophil counts ( 32888494) Eosinophilic esophagitis ( 25017104) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Plasma anti-thyroid peroxidase levels ( 29678681) Pursuit maintenance gain ( 29064472) Refractive error ( 32231278) Systolic blood pressure ( 30578418)
Interacting Genes		376 interacting genes: ABT1 AEBP2 AFDN AKT1 AKT2 ALKBH8 AP1M1 AP1S1 APTX AQP1 ARF1 ARF3 ARHGEF3 ARHGEF5 ARL6IP1 ARMCX1 ASIC1 ASIC2 ATP5IF1 ATXN1L ATXN3 ATXN7 ATXN7L3 AVPI1 BAHD1 BCL2L14 BEX1 BLK BLOC1S2 BOLA3 BRD1 BTG2 BUD31 BYSL C1orf35 C2CD5 C4orf46 C8orf33 CACNA1C CACNA1I CARD9 CBX8 CCDC102B CCDC103 CCDC187 CCNH CDC42EP2 CDC73 CDCA7L CDK2AP1 CDKL3 CDKN2B CDKN2D CEP19 CEP290 CEP57L1 CEP89 CEP95 CGGBP1 CHMP1B CIC COIL CPNE2 CPNE7 CRY2 CSNK2A2 CTNNB1 CTSG CUTC CWF19L2 CYP21A2 DCTD DCUN1D5 DDX55 DDX6 DLG4 DMC1 DMD DNAJB13 DNMT1 DNTTIP1 DNTTIP2 DPF2 DRAP1 DTNB DUSP29 EAF1 EEF2KMT EFHC2 EFNB1 EFNB2 EHD2 EHHADH EIF1AD EIF3D EIF4A3 EIF4EBP1 EIF4H EIF5A ENKD1 EPHB2 EPM2AIP1 ERBB2 ERBIN ESCO2 EXOSC5 F11R FAM161A FAM161B FAM214B FAM219B FAM90A1 FAM9A FBXL3 FBXL8 FGF16 FKBP6 FLYWCH1 FMR1 FXN FXR2 GADD45GIP1 GAS2L2 GFI1 GFI1B GLYCTK GPATCH11 GPATCH2 GPC4 GPKOW GRB10 GRB7 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIP1 GRM3 GRM7 GRXCR1 GTF2E2 GTPBP2 HDAC4 HEXIM2 HMBOX1 HMBS HMG20A HOPX HOXA5 HSD17B14 HSF2 HSF2BP ID2 IHO1 IL16 ILF2 INO80B INO80E INPP5J IP6K1 ISCU JAM3 JRK KAT5 KCTD1 KCTD6 KCTD9 KIAA1328 L3MBTL2 LCLAT1 LCN2 LGALS14 LMO1 LMO3 LONRF1 LRP2BP LRRC73 LZTFL1 LZTS1 MAGEA4 MAGEB4 MAP2K6 MAPK9 MAPRE3 MAZ MBD3 MCM10 MEOX2 MGME1 MID2 MNS1 MOB3C MORF4L1 MORF4L2 MORN3 MOS MRI1 MRNIP MSRB3 MSS51 MTA1 MTG1 NATD1 NCOA5 NDEL1 NECAB2 NECTIN2 NECTIN4 NEK6 NLGN3 NME7 NMNAT1 NOC4L OARD1 OPTN OSBP2 OSGIN1 OSTF1 PAFAH1B3 PAX6 PBX4 PCBD1 PDCD5 PDS5A PEBP1 PHF19 PIBF1 PKN1 PKNOX2 PLEKHA7 PNKP PNO1 POLL POLR3C PPARA PPL PRKCA PRKCG PRKN PRLHR PRPF18 PRPF31 PRPF40A PSMA1 PSME3 PTEN PTRH1 QARS1 RAD51D RASAL3 REEP6 REL RFC3 RIMS3 RIN1 RNF8 RNPS1 ROBO3 ROPN1 RPIA RPP25 RRP8 RXRB RXRG SACS SCAND1 SCNM1 SEMA3B SEPTIN1 SERBP1 SERTAD1 SERTAD3 SH2D4A SH3GLB2 SHFL SLC6A3 SLIRP SLX9 SMARCA2 SMARCB1 SMARCD1 SNRNP25 SNRPA1 SNRPB2 SNW1 SPANXN2 SPATC1L SPEG SSNA1 STK19 STK4 SYT17 TBC1D22B TBC1D26 TBC1D7 TCEA2 TCEANC TCEANC2 TDO2 TEX101 TFIP11 THAP6 THAP7 TLE5 TLNRD1 TPM4 TRAF4 TRAF5 TRIM44 TRIM54 TRIML2 TRMT2A TSC1 TSC2 TSGA10IP TSN TSTD2 TTC23 TTC23L TXNDC9 TXNL4B TYW3 UBE2E3 UBE2K UBQLN4 USHBP1 USP2 USP7 UTP3 VAX1 VEZF1 VPS25 WT1 XPA YES1 YPEL2 YTHDC1 ZBED1 ZBTB2 ZBTB24 ZBTB49 ZFHX3 ZFP2 ZFP91 ZMAT2 ZMYND12 ZNF165 ZNF17 ZNF205 ZNF250 ZNF264 ZNF276 ZNF286A ZNF329 ZNF330 ZNF35 ZNF408 ZNF410 ZNF414 ZNF417 ZNF438 ZNF497 ZNF524 ZNF575 ZNF576 ZNF593 ZNF624 ZNF691 ZNF71 ZNF764 ZNF774 ZSCAN21 ZSCAN23 ZZZ3	293 interacting genes: ABI2 ABLIM1 ACTN3 ADD1 ANAPC16 ANKRD55 ANKS1B ARHGAP45 ARHGEF3 ARHGEF4 ARHGEF5 ARHGEF6 ATXN7L2 BARD1 BAX BAZ2B BCAS2 BEND7 BEX2 BLK BMI1 BYSL C10orf88 C18orf54 C1orf35 C1orf94 C2CD6 C4orf46 C5orf49 C7orf31 C9orf24 CAMSAP3 CARD9 CASS4 CBX8 CBY2 CCDC113 CCDC116 CCDC120 CCDC13 CCDC146 CCDC185 CCDC187 CCDC198 CCDC33 CCHCR1 CCSER1 CDC37 CDC73 CDCA7L CDR2L CDYL2 CEP55 CEP57 CKS1B CLIP4 CNNM1 CNNM3 CNOT2 COIL CTSZ CTTNBP2 CTTNBP2NL CWF19L2 DALRD3 DCDC2B DEFB112 DMAP1 DMRT3 DOCK8 DPF2 DUSP13 EAF1 EIF3D ELOA2 EMD ENKD1 EPHB3 EPM2AIP1 FAM107A FAM110A FAM110B FAM124B FAM161B FAM214B FAM228A FAM90A1 FBXO44 FHL2 FHL3 FLYWCH1 FUT9 GAS2L2 GAS8 GCM2 GEM GGN GNL3L GOLGA1 GPANK1 GPATCH2L GPBP1 GPKOW GPSM3 H2AW HASPIN HCK HDAC4 HEXIM2 HEY2 HNRNPH2 HOMEZ HOXB5 HOXC8 HSF2 IER2 IL16 INO80B INPP5J INSYN2A IPMK IQCC ITGB3BP JRK KANK2 KAT5 KIAA0408 KIF24 KIF5B KIF9 KIFC3 KLF4 L3MBTL2 L3MBTL3 L3MBTL4 LAGE3 LEP LGALS4 LMO4 LNX1 LRRC29 LRRC56 LRRN4 LUZP4 MAGED1 MAGOHB MARCHF7 MEF2A MFAP1 MISP MKRN3 MVB12A MYOZ3 NAB2 NCK2 NFIL3 NHSL2 NME4 NPPA NSMF NTAQ1 NUDT10 NXF1 ODF3B ODF3L2 OPTN P2RX7 PAK6 PAPSS2 PARD6B PDLIM7 PICK1 PKD2 PKN1 PKP1 PLB1 PLEKHA2 PLEKHA7 PNMA5 POGZ POLDIP3 POMC PPM1K PPP1R18 PPP1R32 PRPF18 PRPF3 PRPF31 PRR5L PSMA1 PSTPIP1 RAB11FIP2 RAB36 RAB3IL1 RAD51D RALY RBM17 RBM41 RBM48 RCOR3 REXO4 RIBC1 RIN1 RNF135 RNF169 ROBO3 RPS28 RTP5 SAMD4A SAPCD1 SART1 SAXO1 SCNM1 SDCBP SELENOV SEMA3B SEMA4C SEPTIN1 SEPTIN9 SETDB1 SH2D4A SHFL SHISA6 SIRPA SLAIN1 SLC6A1 SMARCB1 SMARCD1 SMG9 SNAPC1 SNW1 SNX18 SNX21 SPATA22 SPEG SPG7 SPRED1 SPRY1 SYCE1L SYNGAP1 TAB2 TAGAP TASOR2 TBC1D1 TBC1D30 TCEA2 TCF19 TEPSIN TFIP11 THAP6 TMEFF2 TMSB4X TNS4 TOX2 TP53BP2 TRAF5 TRARG1 TSEN15 TSGA10IP TSHZ3 TTC23 TTC9C TULP3 UBE2I UPF2 UPRT USP20 VEZF1 VHL VPS72 WASF1 WASHC1 WDR25 YJU2B ZBTB16 ZBTB42 ZC2HC1C ZCWPW2 ZFC3H1 ZGPAT ZNF185 ZNF250 ZNF417 ZNF511 ZNF564 ZNF581 ZNF587 ZNF648 ZNF688 ZNF774 ZNF835 ZNF84 ZNF844
Entrez ID		9463	11077
HPRD ID		16176	05186
Ensembl ID		ENSG00000100151	ENSG00000160207
Uniprot IDs		A0A024R1J5 Q9NRD5	O75031 Q6IAT7
PDB IDs		2GZV 6AR4 6BJN 6BJO
Enriched GO Terms of Interacting Partners?
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