HOMER3 and ZBTB4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		HOMER3	ZBTB4
Description		homer scaffold protein 3	zinc finger and BTB domain containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Dendrite	Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Methyl-CpG Binding Methyl-CpNpG Binding Protein Kinase Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated
Pathways		Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Brain morphology (MOSTest) ( 32665545) Corpus callosum posterior volume ( 31530798) Diverticular disease ( 30177863) Height ( 25282103 31562340) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Refractive error ( 32231278) Serum uric acid levels ( 30993211) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		92 interacting genes: ABI1 ABI2 ABI3 APP ARL13B C1orf116 C4orf17 CCDC120 CCDC141 CCDC187 CDC37 CDK18 CEBPB CWF19L2 DVL3 DYNLL1 DYNLL2 EAF1 EFHC1 EIF3D FAM161B FAM90A1 FAT1 FBXO28 FMR1 FRYL FXR1 FXR2 GAS8 GDF15 GGN GRM5 HOMER1 HOXB5 INCA1 ITPR1 KANK2 KANK4 KDM1A KRTAP19-7 LHX2 LNX1 LRRC7 LSM14B MDM1 MEOX1 MFAP1 MIA3 MOS MSS51 NEBL NTAQ1 OTX2 PALLD PAX6 PAX7 PKN1 PLAAT5 POLI POM121 PPP1R18 PPP1R32 PRCC PRR35 PSMA1 PSMA2 PSMC5 PSORS1C2 RBM14 RBM22 RUNX1T1 RYR1 SAXO1 SCNM1 SDCBP SHANK3 SLAIN1 SMR3B SNRPF SRPK2 TBC1D22B TOX2 TRPC1 TSC1 USP2 WBP2 WIPF1 ZBTB4 ZNF19 ZNF35 ZNF414 ZNF655	17 interacting genes: ANXA2 BANP CALCOCO2 CBFA2T3 CCDC57 CEP70 CEP76 CYSRT1 GOLGA2 HIPK2 HOMER3 KLHL12 PDE4DIP PIBF1 POU6F2 TP53BP2 TRIM23
Entrez ID		9454	57659
HPRD ID		07270	11693
Ensembl ID		ENSG00000051128	ENSG00000174282
Uniprot IDs		Q9NSC5	B3KVD4 Q9P1Z0
PDB IDs		2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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